21 Aug Discovery Square
Discovery Square is a dynamic, 16-block innovation district in downtown Rochester, developed through the Destination Medical Center (DMC) initiative—a $5.6 billion, 20-year public-private investment plan anchored by Mayo Clinic. Located just 495 steps from the doors of Mayo Clinic’s headquarters, it serves as an urban life-science hub. The district includes One and Two Discovery Square, which opened in 2019 and 2021 respectively, offering cutting-edge lab and office space designed to foster collaboration among Mayo Clinic, startups, researchers, and industry leaders. One Discovery Square is home to tenants from key innovation initiatives at Mayo Clinic, leading industry partners, start-ups, and higher education—creating an environment where collaboration and discovery thrive. Two Discovery Square, Rochester’s first WiredScore-Certified building, features advanced digital infrastructure, flexible lab configurations, imaging support, AI capabilities, and communal spaces that promote innovation. Looking ahead, in 2026 Discovery Square will open two shared lab spaces to support Rochester’s growing start-up economy.
